| 2000 Week 2
- Bye:
- Arizona Cardinals 32, Dallas Cowboys 31 -- Box Score
- Baltimore Ravens 39, Jacksonville Jaguars 36 -- Box Score
- Buffalo Bills 27, Green Bay Packers 18 -- Box Score
- Carolina Panthers 38, San Francisco 49ers 22 -- Box Score
- Cleveland Browns 24, Cincinnati Bengals 7 -- Box Score
- Denver Broncos 42, Atlanta Falcons 14 -- Box Score
- Detroit Lions 15, Washington Redskins 10 -- Box Score
- Minnesota Vikings 13, Miami Dolphins 7 -- Box Score
- New Orleans Saints 28, San Diego Chargers 27 -- Box Score
- New York Giants 33, Philadelphia Eagles 18 -- Box Score
- New York Jets 20, New England Patriots 19 -- Box Score
- Oakland Raiders 38, Indianapolis Colts 31 -- Box Score
- St. Louis Rams 37, Seattle Seahawks 34 -- Box Score
- Tampa Bay Buccaneers 41, Chicago Bears 0 -- Box Score
- Tennessee Titans 17, Kansas City Chiefs 14 (OT) -- Box Score
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